Operative Neurophysiology – 1st Edition by Justin W. Silverstein, Randy S. D’Amico & Jason A. Ellis – 2026 | PDF

Explore the science of surgical neurophysiology, master essential neuromonitoring techniques, and understand how neurological function is assessed during complex operations.

Build a deeper understanding of intraoperative neurophysiological monitoring (IONM) with Operative Neurophysiology, edited by Justin W. Silverstein, Randy S. D’Amico, and Jason A. Ellis.

Designed as a comprehensive reference for surgical neurophysiology, this textbook connects the anatomical and physiological foundations of the nervous system with the practical application of monitoring and mapping techniques used in modern operating rooms.

Intraoperative neurophysiological monitoring plays an important role in procedures involving the brain, spinal cord, cranial nerves, and peripheral nervous system. By analyzing electrical signals and neurological responses during surgery, medical professionals can identify changes in nervous system function that may indicate potential neurological injury.

This first edition presents a structured overview of contemporary neurophysiological techniques, including somatosensory evoked potentials, motor evoked potentials, electromyography, electroencephalography, and functional brain mapping.

The book also examines their application in neurosurgical procedures involving intracranial tumors, cerebrovascular disorders, skull base pathologies, spinal conditions, and peripheral nerve surgery.

Through detailed discussions of clinical anatomy, electrophysiological principles, surgical approaches, and monitoring considerations, this resource supports a comprehensive understanding of the relationship between neurological function and surgical intervention.

Whether you're studying clinical neurophysiology, preparing for specialist training, or expanding your knowledge of intraoperative monitoring, this textbook provides an extensive foundation in operative neurophysiology.

What You'll Learn

• Foundations of Operative Neurophysiology: Understand the neurological and electrophysiological principles underlying intraoperative monitoring and mapping.
• Intraoperative Neurophysiological Monitoring (IONM): Explore monitoring techniques used to evaluate neurological function during complex surgical procedures.
• Somatosensory Evoked Potentials (SSEPs): Learn how sensory pathway responses are recorded and interpreted during surgery.
• Motor Evoked Potentials (MEPs): Examine transcranial and direct cortical stimulation techniques used to assess motor pathways.
• Electromyography (EMG) and Nerve Conduction: Study electrical muscle activity, triggered electromyography, and peripheral nerve assessment.
• Electroencephalography (EEG): Understand the recording and interpretation of cerebral electrical activity during surgical monitoring.
• Electrocorticography (ECoG): Explore direct cortical electrical recordings and their applications in neurosurgical procedures.
• Brain and Language Mapping: Discover techniques used to identify functional brain regions involved in movement, language, and other neurological activities.
• Brainstem Auditory Evoked Potentials: Examine auditory pathway monitoring and its relevance to brainstem and skull base surgery.
• Spinal Reflexes and Brainstem Reflexes: Learn how reflex testing contributes to the evaluation of neurological pathways.
• Supratentorial Brain Surgery: Explore monitoring strategies relevant to cerebral tumor surgery, epilepsy procedures, and deep brain stimulation.
• Cerebrovascular Surgery: Understand neuromonitoring applications in cerebral aneurysm surgery, vascular malformations, intracranial bypass procedures, and carotid endarterectomy.
• Skull Base Surgery: Review neurophysiological monitoring techniques used during operations involving the anterior, middle, and posterior cranial fossae.
• Spinal Surgery and Neuromonitoring: Examine monitoring considerations for cervical, thoracic, and lumbar spinal procedures.
• Spinal Cord and Column Lesions: Explore neurophysiological assessment during surgical treatment of spinal tumors and other structural abnormalities.
• Patient Positioning and Neurological Safety: Understand how surgical positioning can affect peripheral nerves and neurological function.
• Interventional Procedures: Explore the role of neurophysiological techniques in selected interventional radiology procedures.
• Future Developments in IONM: Examine emerging concepts and directions in surgical neurophysiological monitoring.

Why Choose This Textbook?

• Comprehensive Clinical Coverage: Examines fundamental monitoring modalities alongside their applications in complex neurosurgical procedures.
• Practical Surgical Focus: Connects theoretical neurophysiology with real-world monitoring and mapping applications.
• Multidisciplinary Perspective: Integrates the expertise and clinical considerations of surgeons, neurophysiologists, neurologists, and monitoring specialists.
• Extensive Medical Illustrations: Includes 267 illustrations, comprising 239 color images and 28 black-and-white illustrations.
• Detailed Neurophysiological Techniques: Covers major electrophysiological monitoring methods used in operative settings.
• Specialized Surgical Applications: Addresses brain, cerebrovascular, skull base, spinal, and peripheral nerve procedures.
• Neurological Risk Assessment: Explores the interpretation of bioelectrical signal changes and their clinical significance.
• Professional Learning Resource: Suitable for specialist education, advanced clinical study, and continued professional development.
• Structured Scientific Reference: Organizes complex concepts into focused chapters covering monitoring techniques and surgical applications.

Who Is This Book For?

Ideal for neurosurgeons, clinical neurophysiologists, neurologists, medical residents, surgical monitoring specialists, and healthcare professionals seeking a comprehensive understanding of intraoperative neurological monitoring.

This textbook is particularly useful for:

• Neurosurgeons and Neurosurgical Residents seeking to understand neurophysiological monitoring during brain and spine procedures.
• Clinical Neurophysiologists studying electrophysiological techniques and their application during surgery.
• Intraoperative Neuromonitoring Specialists developing their understanding of monitoring modalities and signal interpretation.
• Neurologists and Neurology Trainees exploring the clinical applications of electrophysiology in surgical settings.
• Spine Surgeons and Surgical Trainees studying neurological monitoring during spinal interventions.
• Anesthesiologists seeking a better understanding of neurophysiological responses and the effects of anesthesia on monitoring.
• Advanced Medical Students interested in neuroscience, neurosurgery, and clinical neurophysiology.
• Medical Researchers and Educators requiring a detailed reference for specialist teaching and academic study.

It is particularly valuable for readers who already possess foundational knowledge of anatomy, physiology, and clinical medicine and wish to develop expertise in surgical neurophysiology.

Book Details

• Title: Operative Neurophysiology
• Subtitle: Practical Application for Comprehensive Neuromonitoring and Neuromapping Techniques
• Edition: First Edition
• Editors: Justin W. Silverstein, Randy S. D’Amico, Jason A. Ellis
• Publisher: Springer Nature Switzerland AG
• Imprint: Springer, Cham
• Publication Year: 2026
• ISBN-13 (E-Book): 9783032125712
• Pages: 787, plus 23 preliminary pages
• Chapters: 39
• Illustrations: 267 (239 color, 28 black-and-white)
• Language: English
• Subject: Clinical Neurophysiology, Neurosurgery, Intraoperative Neuromonitoring, Neuromapping, Neuroscience, and Surgical Medicine
• Format: E-book

Develop a deeper understanding of neurological function during surgery and explore the monitoring technologies that support informed clinical decision-making with this comprehensive reference in operative neurophysiology.

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